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ZIRC
ZFIN ID: ZDB-GENE-980526-488
Gene Name: fibroblast growth factor receptor 4
Gene Symbol: fgfr4    Nomenclature History

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Previous Names: etID309818.21 (1), wu:fc13h10 (1), zgc:111935

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have ATP binding activity; fibroblast growth factor binding activity; and fibroblast growth factor-activated receptor activity. Involved in regulation of hematopoietic stem cell differentiation. Predicted to localize to the integral component of plasma membrane and receptor complex. Is expressed in several structures, including brain; cardiovascular system; digestive system; head; and head mesenchyme. Orthologous to human FGFR4 (fibroblast growth factor receptor 4).
Genome Resources: Alliance (1),  Gene:100000160 (1),  Ensembl(GRCz11):ENSDARG00000069105 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu3514 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hu3582 Unknown Unknown Unknown ENU
    la022005Tg Transgenic Insertion Unknown Unknown DNA
    sa6682 Point Mutation Unknown Premature Stop ENU
    sa24004 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24005 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37357 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-fgfr4
    1
    CRISPR2-fgfr4
    1
    MO1-fgfr4 N/A 2
    MO2-fgfr4 N/A 2
    MO3-fgfr4 N/A 1
    DISEASE ASSOCIATED WITH fgfr4 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    {Cancer progression/metastasis}
    DISEASE ASSOCIATED WITH fgfr4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of hematopoietic stem cell differentiation (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function protein binding (more)
    GO Terms (all 24)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fgfr4-201 (1)    Ensembl 5011
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fgfr4 No data available
    MARKER RELATIONSHIPS
    fgfr4 Contained in: [BAC] CH211-281E1 (1) (order this), DKEY-53B2 (1) (order this)
    fgfr4 Contains: [BAC END] zc120k11.ya (1)
    fgfr4 Encodes: [EST] fc13h10 (1)
    [cDNA] cssl:d109 (1), MGC:198431 (1) (order this)
    fgfr4 Has Artifact: [cDNA] MGC:111935 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131430 (1) 4705 bp
    Genomic GenBank:BX649250 (1) 165729 bp
    Select Tool
    Polypeptide UniProtKB:A0A286Y9G6 (1) 923 aa
    Sequence Clusters UniGene:75058 (1)
    Sequence Information (all 25)
    ORTHOLOGY for fgfr4 ( Chr: 21 )
    CITATIONS (92)