ZFIN ID: ZDB-GENE-980526-488
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Gene Name: fibroblast growth factor receptor 4
Gene Symbol: fgfr4
Sequence Ontology ID : SO:0000704

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Previous Names: etID309818.21 (1), wu:fc13h10 (1), zgc:111935

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(Including Attributions)
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 25 figures from 23 publications
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
  anatomical structure, brain, caudal vein plexus, cephalic musculature (all 39) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu3514 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • hu3582 Unknown Unknown Unknown ENU
    la022005Tg Transgenic Insertion Unknown Unknown DNA
    sa6682 Point Mutation Unknown Premature Stop ENU
    sa24004 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa24005 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa37357 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
    • Targeting reagents: CRISPR1-fgfr4 (1), CRISPR2-fgfr4 (1), MO1-fgfr4 (1), MO2-fgfr4 (1), MO3-fgfr4 (1)
    PHENOTYPE
    Data: Fig. 10 from Nakayama et al., 2008
    Observed in: optic cup, solid lens vesicle
    DISEASE ASSOCIATED WITH fgfr4 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    {Cancer progression/metastasis}
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process fibroblast growth factor receptor signaling pathway (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function protein binding (more)
    GO Terms (all 18)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719
  • InterPro:IPR001245
  • InterPro:IPR003598
  • InterPro:IPR003599
  • InterPro:IPR007110
  • InterPro:IPR008266
  • InterPro:IPR011009
  • InterPro:IPR013098
  • InterPro:IPR013151
  • InterPro:IPR013783
  • InterPro:IPR016248
  • InterPro:IPR017441
  • InterPro:IPR020635
    		•
  • PROSITE:PS00107
  • PROSITE:PS00109
  • PROSITE:PS50011
  • PROSITE:PS50835
    		•
  • Pfam:PF00047
  • Pfam:PF07679
  • Pfam:PF07714
    		•
  • EC:2.7.10.1
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA fgfr4-001 (1) 5011
    Select Tool
    ncRNA fgfr4-002 (1) 3229
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM fgfr4 No data available
    MARKER RELATIONSHIPS
    fgfr4Contained in: [BAC] CH211-281E1 (1) (order this), DKEY-53B2 (1) (order this)
    fgfr4Contains: [BAC END] zc120k11.ya (1)
    fgfr4Encodes: [EST] fc13h10 (1)
    [cDNA] cssl:d109 (1), MGC:198431 (1) (order this)
    fgfr4Has Artifact: [cDNA] MGC:111935 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131430 (1) 4705bp
    Select Tool
    Genomic GenBank:BX649250 (1) 165729bp
    Select Tool
    Polypeptide UniProtKB:B7ZVT9 922aa
    Select Tool
    Sequence Clusters UniGene:75058 (1)
    Sequence Information (all 23)
    OTHER fgfr4 GENE PAGES
  • Gene:100000160 (1)
  • VEGA:OTTDARG00000021085 (1)
  • Ensembl(GRCz10):ENSDARG00000069105 (1)
    • ORTHOLOGY for fgfr4 (Chr: 21)
    CITATIONS (80)