header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-980526-403
Gene Name: NK2 homeobox 2a
Gene Symbol: nkx2.2a
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: nk2.2, nkx2-2, nkx2.2, id:ibd5090 (1), wu:fc83b01, zgc:136536

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in endocrine pancreas development and nervous  ...
GENE EXPRESSION
All Expression Data: 143 figures from 90 publications
Directly Submitted Expression Data: 3 figures (3 images) from Kudoh et al., 2001 [ibd5090]
  6 figures (8 images) from Thisse et al., 2004 [IMAGE:6912071]
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23158 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH nkx2.2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nkx2.2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ventral spinal cord interneuron differentiation (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 18)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nkx2.2a-201 (1) 1555
    nkx2.2a-202 (1) 1730
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nkx2.2a
    MARKER RELATIONSHIPS
    nkx2.2aContained in: [BAC] DKEY-89L19 (1) (order this)
    nkx2.2aEncodes: [EST] fc83b01 (1), ibd5090 (1) (order this), IMAGE:6912071 (1) (order this)
    [cDNA] MGC:100783 (1) (order this), MGC:136536 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131422 (1) 1576bp
    Genomic GenBank:BX927409 (1) 154287bp
    Select Tool
    Polypeptide UniProtKB:F1QNE4 (1) 273aa
    Sequence Clusters UniGene:75083 (1)
    Sequence Information (all 22)
    ORTHOLOGY for nkx2.2a (Chr: 17)
    CITATIONS (162)