Gene
nkx2.2a
- ID
- ZDB-GENE-980526-403
- Name
- NK2 homeobox 2a
- Symbol
- nkx2.2a Nomenclature History
- Previous Names
-
- nk2.2
- nkx2-2
- nkx2.2
- id:ibd5090 (1)
- wu:fc83b01
- zgc:136536
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within endocrine pancreas development; floor plate formation; and neurogenesis. Predicted to be active in nucleus. Is expressed in several structures, including digestive system; nervous system; neural keel; neural rod; and neural tube. Orthologous to human NKX2-2 (NK2 homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 151 figures from 96 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6912071 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 13 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homeobox, conserved site | Homeobox domain | Homeobox domain, metazoa | Homeobox-like domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q90481
|
269 | ||||
|
UniProtKB:F1QNE4
|
273 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
nkx2.2a-201
(1)
|
1555 nt | |
| mRNA |
nkx2.2a-202
(1)
|
1730 nt |
Interactions and Pathways
No data available
Plasmids
No data available