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ZIRC
ZFIN ID: ZDB-GENE-980526-375
Gene Name: transforming growth factor beta receptor 2b
Gene Symbol: tgfbr2b
Sequence Ontology ID : SO:0000704

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Previous Names: tgfbr2, cb537 (1), TGF-beta receptor 2, wu:fj05c10, zgc:110498 (1)

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have several functions, including SMAD binding activity; transforming growth factor beta receptor activity, type II; and type I transforming growth factor beta receptor binding activity.  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027754Tg Transgenic Insertion Unknown Unknown DNA
Targeting reagents:
DISEASE ASSOCIATED WITH tgfbr2b HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
esophageal cancer Esophageal cancer, somatic 133239
hereditary nonpolyposis colorectal cancer type 6 Colorectal cancer, hereditary nonpolyposis, type 6 614331
Loeys-Dietz syndrome 2 Loeys-Dietz syndrome 2 610168
DISEASE ASSOCIATED WITH tgfbr2b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process hematopoietic stem cell differentiation (more)
Cellular Component integral component of membrane (more)
Molecular Function ATP binding (more)
GO Terms (all 28)
TRANSCRIPTS
Type Name Length (bp) Analysis
ncRNA tgfbr2-002 (1) 400
mRNA tgfbr2b-201 (1) 2252
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIESNo data available
PLASMIDSNo data available
CONSTRUCTS WITH SEQUENCES FROM tgfbr2b No data available
MARKER RELATIONSHIPS
tgfbr2bContained in: [BAC] DKEY-28F6 (1) (order this), DKEY-239I15 (1) (order this)
tgfbr2bContains: [SNP] rs3728806 (1), rs3728807 (1), rs3728808 (1)
tgfbr2bEncodes: [EST] cb537 (1) (order this), fj05c10 (1)
[cDNA] MGC:110498 (1) (order this), MGC:192403 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_182855 (1) 2275bp
Genomic GenBank:CR848052 (1) 189151bp
Select Tool
Polypeptide UniProtKB:F1QKF4 (1) 556aa
Sequence Clusters UniGene:77521 (1)
Sequence Information (all 20)
ORTHOLOGY for tgfbr2b (Chr: 16)
CITATIONS (45)