Gene

hoxa13b

ID
ZDB-GENE-980526-365
Name
homeobox A13b
Symbol
hoxa13b Nomenclature History
Previous Names
  • Hoxa-13
  • wu:fa66g07
  • zgc:110514
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in Guttmacher syndrome and hand-foot-genital syndrome. Is expressed in several structures, including chondroblast; pectoral fin; pectoral fin bud; pectoral fin field; and tail bud. Orthologous to human HOXA13 (homeobox A13).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
19 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hoxa13b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Guttmacher syndrome Alliance ?Guttmacher syndrome 176305
hand-foot-genital syndrome Alliance Hand-foot-uterus syndrome 140000
Associated With hoxa13b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR022067 Homeobox protein Hox1A3 N-terminal
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily Homeobox protein Hox1A3 N-terminal
UniProtKB:B5DDS3 274
UniProtKB:P79724 289
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations