ZFIN ID: ZDB-GENE-980526-352
Gene Name: wingless-type MMTV integration site family, member 4a
Gene Symbol: wnt4a
Sequence Ontology ID : SO:0000704

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Previous Names: wnt4, ZfWnt4 (1), zgc:136737

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Location: Chr: 11 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 24 figures from 15 publications
Directly Submitted Expression Data: 6 figures (12 images) from Thisse et al., 2005 [eu648]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  alar plate midbrain region, diencephalon, epiphysis, floor plate (all 30) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh294 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • China Zebrafish Resource Center (CZRC) (order this)
  • fh295 Point Mutation Unknown Unknown ENU
    sa14222 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • wnt4a_unrecovered Point Mutation Unknown Unknown ENU
    Targeting reagents: MO1-wnt4a (1), MO2-wnt4a (1), MO3-wnt4a (1), MO4-wnt4a (1)
    PHENOTYPE
    Data: 5 figures from 4 publications
    Observed in: ceratobranchial cartilage, convergent extension, embryonic viscerocranium morphogenesis, habenular commissure axon extension involved in axon guidance (all 8) expand
    DISEASE ASSOCIATED WITH wnt4a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    46 XX gonadal dysgenesis SERKAL syndrome 611812
    Mullerian aplasia and hyperandrogenism 158330
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of transcription, DNA-templated (more)
    Cellular Component extracellular region (more)
    Molecular Function receptor binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR005817 (1)
  • InterPro:IPR009142 (1)
  • InterPro:IPR018161 (1)
  • PROSITE:PS00246 (1)
  • Pfam:PF00110 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA wnt4a-001 (1) 2242
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM wnt4a
    Tg(UAS:wnt4a,cryaa:Cerulean)
    MARKER RELATIONSHIPS
    wnt4aContained in: [BAC] CH211-146F2 (1) (order this), DKEY-208K8 (1) (order this)
    wnt4aContains: [SNP] rs3728403 (1)
    wnt4aEncodes: [EST] eu648 (1)
    [cDNA] MGC:136737 (1) (order this), MGC:194977 (1) (order this), MGC:194994 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001040387 (1) 2264bp
    Genomic GenBank:CR926911 158622bp
    Select Tool
    Polypeptide UniProtKB:A0A0B5JFI1 (1) 352aa
    Sequence Clusters UniGene:385 (1)
    Sequence Information (all 31)
    OTHER wnt4a GENE PAGES
  • Alliance (1)
  • Gene:30123 (1)
  • VEGA:OTTDARG00000035517 (1)
  • Ensembl(GRCz10):ENSDARG00000071208 (1)
  • ORTHOLOGY for wnt4a (Chr: 11)
    CITATIONS (61)