ZFIN ID: ZDB-GENE-980526-307
Gene Name: ret proto-oncogene receptor tyrosine kinase
Gene Symbol: ret
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: c-ret (1), cret, etID315074.13 (1), ret1, wu:fd13h01

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 37 figures from 26 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
PHENOTYPE
Data: 15 figures from 9 publications
Observed in:
DISEASE ASSOCIATED WITH ret HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
congenital central hypoventilation syndrome Central hypoventilation syndrome, congenital 209880
familial medullary thyroid carcinoma Medullary thyroid carcinoma 155240
multiple endocrine neoplasia type 2A Multiple endocrine neoplasia IIA 171400
multiple endocrine neoplasia type 2B Multiple endocrine neoplasia IIB 162300
phaeochromocytoma Pheochromocytoma 171300
{Hirschsprung disease, susceptibility to, 1} 142623
GENE ONTOLOGY
Ontology GO Term
Biological Process enteric nervous system development (more)
Cellular Component membrane (more)
Molecular Function protein binding (more)
GO Terms (all 20)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR001245 (1)
  • InterPro:IPR002126 (1)
  • InterPro:IPR008266 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR015919 (1)
  • InterPro:IPR016249 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR020635 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00109 (1)
  • PROSITE:PS50011 (1)
  • Pfam:PF00028 (1)
  • Pfam:PF07714 (1)
  • EC:2.7.10.1 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ret-001 (1) 4230
    ret-002 (1) 5094
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ret
    MARKER RELATIONSHIPS
    retContained in: [BAC] DKEY-192P21 (1) (order this)
    retEncodes: [EST] fd13h01
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_181662 (1) 4145bp
    Genomic GenBank:AC124155 (1) 173037bp
    Select Tool
    Polypeptide UniProtKB:A8E7C6 (1) 1106aa
    Sequence Clusters UniGene:75763 (1)
    Sequence Information (all 24)
    OTHER ret GENE PAGES
  • Alliance (1)
  • Gene:30512 (1)
  • VEGA:OTTDARG00000017726 (1)
  • Ensembl(GRCz10):ENSDARG00000055305 (1)
  • ORTHOLOGY for ret (Chr: 13)
    CITATIONS (83)