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ZIRC
ZFIN ID: ZDB-GENE-980526-306
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Gene Name: muscle segment homeobox 3
Gene Symbol: msx3
Sequence Ontology ID : SO:0000704

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Previous Names: msx-c, msxc (1), etID309953.13 (1), msh-C, mshC, zgc:86596 (1)

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have sequence-specific DNA binding activity; involved in otic placode formation; predicted to localize to the nucleus; orthologous to human MSX2 (msh homeobox 2).
GENE EXPRESSION
All Expression Data: 69 figures from 44 publications
Directly Submitted Expression Data: 7 figures (19 images) from Thisse et al., 2005 [eu507]
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb246 Indel Exon 1 Unknown CRISPR
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
    • mn0245Gt Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • tud18Gt Transgenic Insertion Exon 1 Unknown DNA
  • European Zebrafish Resource Center (EZRC) (order this)
    • Targeting reagents:
    PHENOTYPE
    Data: 2 figures from Phillips et al., 2006
    Observed in:
    DISEASE ASSOCIATED WITH msx3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH msx3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process otic placode formation (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR020479 (1)
    		•
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
    		•
  • Pfam:PF00046 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA msx3-201 (1) 2028
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM msx3
    MARKER RELATIONSHIPS
    msx3Contained in: [BAC] CH211-217G15 (1) (order this), DKEYP-85D1
    msx3Encodes: [EST] eu507 (1), fc66g03 (1)
    [cDNA] MGC:86596 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131272 (1) 944bp
    Select Tool
    Genomic GenBank:CR589879 201310bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q6IQV1 (1) 274aa
    Select Tool
    Sequence Clusters UniGene:32741 (1)
    Sequence Information (all 24)
    OTHER msx3 GENE PAGES
  • Alliance (1)
  • Gene:30526 (1)
  • VEGA:OTTDARG00000001892 (1)
  • Ensembl(GRCz11):ENSDARG00000015674 (2)
    • ORTHOLOGY for msx3 (Chr: 13)
    CITATIONS (104)