ZFIN ID: ZDB-GENE-980526-299
Gene Name: hematopoietically expressed homeobox
Gene Symbol: hhex
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Predicted to have DNA-binding activity transcription repressor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity; involved in several  ...
GENE EXPRESSION
All Expression Data: 97 figures from 57 publications
Wild-type Stages, Structures: Blastula:30%-epiboly (4.66h-5.25h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
s721 Insertion Unknown Frameshift, Premature Stop TALEN
s722 Small Deletion Unknown Inframe Deletion TALEN
Targeting reagents:
PHENOTYPE
Data: 4 figures from 3 publications
Observed in:
DISEASE ASSOCIATED WITH hhex HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH hhex VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of transcription by RNA polymerase II (more)
Cellular Component nucleus (more)
Molecular Function sequence-specific DNA binding (more)
GO Terms (all 23)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR020479 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM hhex
    MARKER RELATIONSHIPS
    hhexEncodes: [cDNA] MGC:193885 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_130934 (1)
    Genomic GenBank:CABZ01081547 (1) 7000bp
    Polypeptide UniProtKB:B3DH15 (1) 228aa
    Sequence Clusters UniGene:79053 (1)
    Sequence Information (all 18)
    OTHER hhex GENE PAGES
  • Alliance (1)
  • Gene:30098 (1)
  • Ensembl(GRCz11):ENSDARG00000098231 (1)
  • ORTHOLOGY for hhex (Chr: 12)
    CITATIONS (206)