Gene

hhex

ID
ZDB-GENE-980526-299
Name
hematopoietically expressed homeobox
Symbol
hhex Nomenclature History
Previous Names
  • hex
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; positive regulation of endothelial cell differentiation; and vasculature development. Predicted to localize to nucleus. Is expressed in several structures, including cardiovascular system; digestive system; endocrine system; hepatoblast; and mesoderm. Orthologous to human HHEX (hematopoietically expressed homeobox).
Genome Resources
Note
None
Expression
All Expression Data
110 figures from 64 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
17 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hhex Human Ortholog
No data available
Associated With hhex Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR020479 Homeobox domain, metazoa
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox domain, metazoa Homeobox-like domain superfamily
UniProtKB:A0A0G2KXR6
UniProtKB:B3DH15 228
UniProtKB:Q9IAV3 228
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations