Publication	Data		Fish	Anatomy
Villasenor et al., 2019	Fig. 1		hhexs721/s721; nim5Tg ,   hhexs721/s721 ,   hhexs721/s721; as3Tg	exocrine pancreas ptf1a expression absent, abnormal intestinal bulb primordium ptf1a expression absent, abnormal liver decreased size, abnormal liver hypoplastic, abnormal pancreas absent, abnormal
	Fig. 2		hhexs721/s721; s870Tg ,   hhexs721/s721	common bile duct ab-2f11 labeling absent, abnormal common bile duct absent, abnormal cystic duct absent, abnormal digestive system duct ab-2f11 labeling absent, abnormal digestive system duct absent, abnormal digestive system duct hepaticobiliary system development decreased occurrence, abnormal extrahepatic duct malformed, abnormal extrapancreatic duct ab-2f11 labeling absent, abnormal extrapancreatic duct ab-2f11 labeling decreased amount, abnormal gall bladder ab-2f11 labeling absent, abnormal gall bladder absent, abnormal intestinal bulb decreased thickness, abnormal
	Fig. 3		hhexs721/s721	anterior pancreatic bud prox1a expression decreased amount, abnormal anterior pancreatic bud sox9b expression absent, abnormal digestive system duct prox1a expression decreased amount, abnormal digestive system duct sox9b expression absent, abnormal liver prox1a expression decreased amount, abnormal liver sox9b expression absent, abnormal
	Fig. 5		s870Tg + MO1-hhex	digestive system duct hepaticobiliary system development process quality, abnormal
	Fig. S1		hhexs721/s721 ,   hhexs721/s721; gz19Tg	pancreatic A cell increased amount, abnormal pancreatic B cell increased amount, abnormal pancreatic D cell decreased amount, abnormal
	Fig. S4		hhexs721/s721	primary islet cell ab-2f11 labeling mislocalised, abnormal
	text only		hhexs721/s721 ,   hhexs722/s722	whole organism decreased life span, abnormal
Gao et al., 2018	Fig. 1		hhexzju16/zju16	exocrine pancreas prss1 expression absent, abnormal exocrine pancreas absent, abnormal liver fabp10a expression decreased distribution, abnormal liver prox1a expression decreased distribution, abnormal liver decreased size, abnormal
	Fig. 3		hhexzju16/zju16; gz15Tg ,   hhexzju16/zju16; zju18Tg	liver morphology, abnormal
	Fig. 4		hhexzju16/zju16 ,   hhexzju16/zju16; zf3097Tg	extrahepatic duct ab-2f11 labeling absent, abnormal extrahepatic duct absent, abnormal gall bladder duct ab-2f11 labeling absent, abnormal gall bladder duct absent, abnormal hepatic duct ab-2f11 labeling absent, abnormal intrahepatic bile duct intestine lumen fabp2 expression mislocalised, abnormal intrahepatic bile duct intestine lumen EGFP expression mislocalised, abnormal liver EGFP expression mislocalised, abnormal
	Fig. 6		hhexzju16/zju16	intestinal bulb cdx1b expression spatial pattern, abnormal intestinal bulb primordium cdx1b expression spatial pattern, abnormal intestinal bulb primordium hhex expression absent, abnormal intestine left side pdx1 expression mislocalised, abnormal liver pdx1 expression mislocalised, abnormal liver primordium pdx1 expression mislocalised, abnormal pancreatic duct pdx1 expression absent, abnormal
	Fig. 8		hhexzju16/zju16	digestive system duct sox9b expression absent, abnormal liver pdx1 expression mislocalised, abnormal
	Fig. S1		hhexzju17/zju17	exocrine pancreas absent, abnormal liver decreased size, abnormal
	Fig. S2		hhexzju16/zju16; zju18Tg	liver morphology, abnormal
Gauvrit et al., 2018	Fig. 1		hhexs722/s722; nz101Tg ,   hhexs721/s721; nz101Tg	facial lymphatic vessel decreased amount, abnormal intersegmental vessel absent, abnormal pericardium edematous, abnormal posterior cardinal vein sprouting angiogenesis disrupted, abnormal trunk lymph vessel absent, abnormal trunk vasculature morphology, abnormal
	Fig. 2		hhexs722/s722; s843Tg ,   hhexs722/s722 ,   hhexs722/s722; nz101Tg	intersegmental vessel absent, abnormal posterior cardinal vein flt4 expression decreased amount, abnormal posterior cardinal vein vegfc expression increased amount, abnormal thoracic duct intersegmental vessel absent, abnormal trunk lymph vessel absent, abnormal trunk vasculature morphology, abnormal
	Fig. 3		hhexs722/s722; nim5Tg ,   hhexs722/s722; nim5Tg; s843Tg ,   hhexs722/s722	endothelial cell ab7-prox1 labeling decreased amount, abnormal endothelial cell TagRFP expression decreased amount, abnormal posterior cardinal vein endothelial cell decreased amount, abnormal somite endothelial cell decreased amount, abnormal
	Fig. 4		hhexs722/s722	intersegmental vessel absent, abnormal thoracic duct intersegmental vessel absent, abnormal
	Fig. S1		hhexs722/s722; y7Tg ,   hhexs721/s721; y7Tg ,   hhexs722/s722; nz101Tg; s843Tg ,   hhexs721/s721; nz101Tg; s843Tg	posterior cardinal vein sprouting angiogenesis disrupted, abnormal primordial hindbrain channel immature, abnormal somite intersegmental vein decreased amount, abnormal thoracic duct intersegmental vessel absent, abnormal
	Fig. S2		hhexs722/s722; nz101Tg	facial lymphatic vessel decreased amount, abnormal otolithic lymph vessel decreased amount, abnormal
	Fig. S4		hhexs722/s722	endothelial cell hhex expression increased amount, abnormal
	Fig. S7		hhexs722/s722	whole organism flt4 expression decreased amount, abnormal whole organism hhex expression increased amount, abnormal whole organism prox1a expression decreased amount, abnormal whole organism vegfc expression increased amount, abnormal
O'Hare et al., 2016	Fig. S3		jh1Tg; jh2Tg + MO3-hhex	exocrine pancreas absent, abnormal exocrine pancreas development arrested, abnormal
Her et al., 2003	Fig. 5		as3Tg + MO1-hhex	liver decreased size, abnormal liver development disrupted, abnormal