ZFIN ID: ZDB-GENE-980526-249
Gene Name: wingless-type MMTV integration site family, member 11
Gene Symbol: wnt11    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: wnt11f1 (2), wnt11r (1), fk73h04, wnt11 family member 1 (2), wu:fk73h04

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have cytokine activity and frizzled binding activity. Involved in embryonic morphogenesis and pharyngeal system development. Predicted to localize to extracellular space. Is expressed in several structures, including cardiovascular system; fin; mesoderm; nervous system; and pharyngeal arch. Orthologous to human WNT11 (Wnt family member 11).
Genome Resources: Alliance (1),  Gene:30283 (1),  Ensembl(GRCz11):ENSDARG00000014796 (2)
Note: From Postlethwait et al. (2019) "analysis of phylogenies and conserved syntenies from sequenced genomes clarifies the evolutionary history and nomenclature of the Wnt11 gene family to better connect teleost models of human disease to human biology."
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh224 Point Mutation Unknown Premature Stop ENU
  • China Zebrafish Resource Center (CZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • fh225 Point Mutation Unknown Unknown ENU
    sa2545 Point Mutation Unknown Premature Stop ENU
    sa27632 Point Mutation Unknown Splice Site ENU
    wnt11_unrecovered Point Mutation Unknown Unknown ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-wnt11 N/A 2
    MO2-wnt11 N/A 1
    MO3-wnt11 N/A 1
    DISEASE ASSOCIATED WITH wnt11 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH wnt11 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic viscerocranium morphogenesis (more)
    Cellular Component extracellular region (more)
    Molecular Function signaling receptor binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA wnt11r-201 (1)    Ensembl 2171
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM wnt11
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(nkx2.5:wnt11,myl7:EGFP) myl7nkx2.5 EGFPwnt11 Danio rerio 1 3
    Tg(UAS:wnt11,cryaa:Cerulean) cryaaUAS Ceruleanwnt11 Danio rerio 1 3
    MARKER RELATIONSHIPS
    wnt11 Contained in: [BAC] DKEY-250D21 (1) (order this)
    wnt11 Encodes: [EST] eu556 (1), fb16b06 (1) (order this), fk73h04
    [cDNA] MGC:76804 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131076 (1) 2169 nt
    Genomic GenBank:CU467651 (1) 107142 nt
    Select Tool
    Polypeptide UniProtKB:A0A0B5JSD6 (1) 352 aa
    Sequence Information (all 17)
    ORTHOLOGY for wnt11 ( Chr: 10 )
    CITATIONS (67)