ZFIN ID: ZDB-GENE-980526-235
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.
Gene Name: twist2
Gene Symbol: twist2
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: dermo1, zgc:101904 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 28 figures from 14 publications
Directly Submitted Expression Data: 7 figures (19 images) from Thisse et al., 2004 [MGC:101904]
Wild-type Stages, Structures: Blastula:1k-cell (3.0h-3.33h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  artery, axial chorda mesoderm, axial mesoderm, axial vasculature (all 28) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: CRISPR1-twist2 (1), CRISPR2-twist2 (1), CRISPR3-twist2 (1), MO1-twist2 (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH twist2 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
ablepharon macrostomia syndrome Ablepharon-macrostomia syndrome 200110
Barber-Say syndrome Barber-Say syndrome 209885
Focal facial dermal dysplasia 3, Setleis type 227260
GENE ONTOLOGY
Ontology GO Term
Molecular Function protein dimerization activity (more)
GO Terms (all 1)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011598
  • InterPro:IPR015789
    		•
  • PROSITE:PS50888
    		•
  • Pfam:PF00010
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA twist2-001 (1) 1227
    Select Tool
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM twist2 No data available
    MARKER RELATIONSHIPS
    twist2Contained in: [BAC] CH73-282H7 (1) (order this)
    twist2Encodes: [cDNA] MGC:101904 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001005956 (1) 1051bp
    Select Tool
    Genomic GenBank:CU929427 (1) 58358bp
    Select Tool
    Polypeptide UniProtKB:Q5XJI8 163aa
    Select Tool
    Sequence Clusters UniGene:36752 (1)
    Sequence Information (all 11)
    OTHER twist2 GENE PAGES
  • Gene:30395 (1)
  • VEGA:OTTDARG00000032844 (1)
  • Ensembl(GRCz10):ENSDARG00000078266 (1)
    • ORTHOLOGY for twist2 (Chr: 9)
    CITATIONS (38)