Gene

cdh11

ID
ZDB-GENE-980526-170
Name
cadherin 11, type 2, OB-cadherin (osteoblast)
Symbol
cdh11 Nomenclature History
Previous Names
  • cdhvn
  • ventral neural cadherin
  • vnc
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have cadherin binding activity and calcium ion binding activity. Involved in otolith development; retina development in camera-type eye; and retinal ganglion cell axon guidance. Predicted to localize to adherens junction and catenin complex. Is expressed in cleithrum; nervous system; optic vesicle; and pectoral fin bud. Human ortholog(s) of this gene implicated in Elsahy-Waters syndrome. Orthologous to human CDH11 (cadherin 11).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdh11 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Elsahy-Waters syndrome Alliance Elsahy-Waters syndrome 211380
Associated With cdh11 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020894 Cadherin conserved site
Domain IPR000233 Cadherin, cytoplasmic domain
Domain IPR002126 Cadherin-like
Family IPR039808 Cadherin
Homologous_superfamily IPR015919 Cadherin-like superfamily
Homologous_superfamily IPR027397 Catenin binding domain superfamily
Domain Details Per Protein
Protein Length Cadherin Cadherin conserved site Cadherin, cytoplasmic domain Cadherin-like Cadherin-like superfamily Catenin binding domain superfamily
UniProtKB:B3DGG4 800
UniProtKB:Q90425 519
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cdh11 polyclonal Rabbit
  • IHC
  • WB
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations