ZFIN ID: ZDB-GENE-980526-168
Gene Name: cyclin E1
Gene Symbol: ccne1    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: ccne (1), cyce (1), fa18e07, wu:fa18e07 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Exhibits kinase activity. Predicted to contribute to protein kinase activity. Predicted to be involved in G1/S transition of mitotic cell cycle and regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to localize to several cellular components, including centrosome; cyclin E1-CDK2 complex; and nucleus. Human ortholog(s) of this gene implicated in breast adenocarcinoma. Is expressed in anterior axial hypoblast; intestine; nervous system; notochord; and polster. Orthologous to human CCNE1 (cyclin E1).
Genome Resources: Alliance (1),  Gene:30188 (1),  Ensembl(GRCz11):ENSDARG00000098622 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa8454 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17090 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25369 Point Mutation Unknown Splice Site ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ccne1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ccne1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell cycle (more)
    Cellular Component host cell nucleus (more)
    Molecular Function kinase activity (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ccne1-201 (1)    Ensembl 2372
    ccne1-203 (1)    Ensembl 2114
    ncRNA ccne1-003 (1) 701
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ccne1 No data available
    MARKER RELATIONSHIPS
    ccne1 Contained in: [BAC] CH211-260E23 (1), DKEY-56M16 (1) (order this)
    ccne1 Contains: [SNP] rs3728087 (1), rs3728088 (1)
    [STS] chunp6695
    ccne1 Encodes: [EST] fa18e07 (1)
    [cDNA] MGC:55274 (1), MGC:86595 (1), MGC:191895 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_130995 (1) 2102 nt
    Genomic GenBank:CR847947 (1) 205682 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4IZF8 (1) 410 aa
    Sequence Information (all 26)
    ORTHOLOGY for ccne1 ( Chr: 7 )
    CITATIONS (82)