Gene
ednrba
- ID
- ZDB-GENE-980526-16
- Name
- endothelin receptor Ba
- Symbol
- ednrba Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have endothelin receptor activity. Involved in iridophore differentiation and regulation of developmental pigmentation. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in ABCD syndrome; Hirschsprung's disease; Waardenburg's syndrome (multiple); asthma; and pulmonary hypertension. Is expressed in gill; head; iridophore; pigment cell; and trunk. Orthologous to human EDNRB (endothelin receptor type B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 19 figures from 8 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ABCD syndrome | Alliance | ?ABCD syndrome | 600501 |
| Waardenburg syndrome type 4A | Alliance | Waardenburg syndrome, type 4A | 277580 |
| {Hirschsprung disease, susceptibility to, 2} | 600155 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Endothelin receptor B | Endothelin receptor family | GPCR, rhodopsin-like, 7TM | G-protein coupled endothelin receptor | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|---|
|
UniProtKB:Q9DGM2
|
426 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA | ednrba-001 (1) | Havana | 1,492 nt | ||
| mRNA |
ednrba-201
(1)
|
Ensembl | 1,489 nt |
Interactions and Pathways
No data available
Plasmids
No data available