Gene

ednrba

ID
ZDB-GENE-980526-16
Name
endothelin receptor Ba
Symbol
ednrba Nomenclature History
Previous Names
  • ednrb1 (1)
  • ednrb1a
  • ros (2)
  • rose
  • rse
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have endothelin receptor activity. Involved in iridophore differentiation and regulation of developmental pigmentation. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in gill; head; iridophore; pigment cell; and trunk. Human ortholog(s) of this gene implicated in ABCD syndrome; Hirschsprung's disease; Waardenburg's syndrome (multiple); asthma; and pulmonary hypertension. Orthologous to human EDNRB (endothelin receptor type B).
Genome Resources
Note
None
Expression
All Expression Data
11 figures from 11 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
16 figures from 7 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ednrba Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
ABCD syndrome Alliance ABCD syndrome 600501
Waardenburg syndrome type 4A Alliance Waardenburg syndrome, type 4A 277580
{Hirschsprung disease, susceptibility to, 2} 600155
Associated With ednrba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR000499 Endothelin receptor family
Family IPR001112 Endothelin receptor B
Domain Details Per Protein
Protein Length Endothelin receptor B Endothelin receptor family GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like
UniProtKB:Q9DGM2 426
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations