Gene

inf2

ID
ZDB-GENE-140711-5
Name
inverted formin 2
Symbol
inf2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Involved in several processes, including glomerular filtration; glomerular visceral epithelial cell development; and slit diaphragm assembly. Is expressed in several structures, including blood vessel; digestive system; eye; pronephros; and somite. Used to study glomerulosclerosis. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate E and focal segmental glomerulosclerosis 5. Orthologous to human INF2 (inverted formin 2).
Genome Resources
Note
None
Expression
All Expression Data
from Sun et al., 2014
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With inf2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Charcot-Marie-Tooth disease dominant intermediate E Alliance Charcot-Marie-Tooth disease, dominant intermediate E 614455
focal segmental glomerulosclerosis 5 Alliance Glomerulosclerosis, focal segmental, 5 613237
Associated With inf2 Via Experimental Models
Human Disease Fish Conditions Citations
glomerulosclerosis WT + MO1-inf2 standard conditions Sun et al., 2014
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-inf2 polyclonal Rabbit
  • IHC
Sigma-Aldrich
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Citations