Gene

adamts16

ID
ZDB-GENE-130530-760
Name
ADAM metallopeptidase with thrombospondin type 1 motif, 16
Symbol
adamts16 Nomenclature History
Previous Names
  • zmp:0000000757 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have metal ion binding activity and metalloendopeptidase activity. Involved in basement membrane disassembly and closure of optic fissure. Predicted to localize to extracellular region. Is expressed in several structures, including digestive system; eye; muscle; optic cup; and pleuroperitoneal region. Used to study coloboma.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Cao et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adamts16 Human Ortholog
No data available
Associated With adamts16 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001590 Peptidase M12B, ADAM/reprolysin
Domain IPR002870 Peptidase M12B, propeptide
Domain IPR010294 ADAMTS/ADAMTS-like, Spacer 1
Domain IPR010909 PLAC
Domain IPR041645 ADAMTS, cysteine-rich domain 2
Domain IPR045371 ADAMTS/ADAMTS-like, cysteine-rich domain 3
Family IPR013273 ADAMTS/ADAMTS-like
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
Homologous_superfamily IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
Repeat IPR000884 Thrombospondin type-1 (TSP1) repeat
Domain Details Per Protein
Protein Length ADAMTS/ADAMTS-like ADAMTS/ADAMTS-like, cysteine-rich domain 3 ADAMTS/ADAMTS-like, Spacer 1 ADAMTS, cysteine-rich domain 2 Metallopeptidase, catalytic domain superfamily Peptidase M12B, ADAM/reprolysin Peptidase M12B, propeptide PLAC Thrombospondin type-1 (TSP1) repeat Thrombospondin type-1 (TSP1) repeat superfamily
UniProtKB:E7FFX0 1224
Transcripts
Genome Browsers
No data available
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-adamts16 polyclonal IgG Rabbit
  • WB
Abcam plc
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations