Gene

unc93b1

ID
ZDB-GENE-130424-1
Name
unc-93 homolog B1, TLR signaling regulator
Symbol
unc93b1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have Toll-like receptor binding activity. Involved in regulation of toll-like receptor signaling pathway. Predicted to localize to endosome and lysosome. Is expressed in heart; liver; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human UNC93B1 (unc-93 homolog B1, TLR signaling regulator).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Yeh et al., 2013
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With unc93b1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 1} 610551
Associated With unc93b1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR010291 Ion channel regulatory protein, UNC-93
Family IPR043268 Protein unc-93 homolog B1
Homologous_superfamily IPR036259 MFS transporter superfamily
Domain Details Per Protein
Protein Length Ion channel regulatory protein, UNC-93 MFS transporter superfamily Protein unc-93 homolog B1
UniProtKB:A7MBX7 369
UniProtKB:F1QYA8 623
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations