ZFIN ID: ZDB-GENE-130424-1
Gene Name: unc-93 homolog B1, TLR signaling regulator
Gene Symbol: unc93b1    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have Toll-like receptor binding activity. Involved in regulation of toll-like receptor signaling pathway. Predicted to localize to endosome and lysosome. Is expressed in heart; liver; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human UNC93B1 (unc-93 homolog B1, TLR signaling regulator).
Genome Resources: Alliance (1),  Gene:100000934 (1),  Ensembl(GRCz11):ENSDARG00000069114 (2)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH unc93b1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 1} 610551
DISEASE ASSOCIATED WITH unc93b1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of toll-like receptor signaling pathway (more)
Cellular Component integral component of membrane (more)
Molecular Function Toll-like receptor binding (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA unc93b1-202 (1)    Ensembl 2489
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM unc93b1 No data available
MARKER RELATIONSHIPS
unc93b1 Contained in: [BAC] CH211-180L22 (1), DKEY-224I13 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001288816 (1) 2375 nt
Genomic GenBank:CR381666 (1) 73281 nt
Select Tool
Polypeptide UniProtKB:F1QYA8 (1) 623 aa
Sequence Information (all 17)
ORTHOLOGY for unc93b1 ( Chr: 1 )
CITATIONS (20)