ZFIN ID: ZDB-GENE-130405-1
Gene Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
Gene Symbol: agap1    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have several functions, including GTP binding activity; GTPase activator activity; and GTPase activity. Predicted to be involved in signal transduction. Predicted to localize to nucleus. Is expressed in cardiac ventricle. Orthologous to several human genes including AGAP1 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 1).
Genome Resources: Alliance (1),  Gene:100148154 (1),  Ensembl(GRCz11):ENSDARG00000062123 (1)
GENE EXPRESSION
All Expression Data: Fig. 6 from Singh et al., 2016
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa14894 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-agap1 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH agap1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH agap1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process signal transduction (more)
    Cellular Component membrane (more)
    Molecular Function GTPase activator activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA agap1-201 (1)    Ensembl 4149
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM agap1 No data available
    MARKER RELATIONSHIPS
    agap1 Contained in: [BAC] CH211-194E2 (1), DKEY-30F11 (1) (order this), DKEY-164N22 (1) (order this), DKEYP-53F11 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_001921491 (1)
    Genomic GenBank:CR847983 (1) 199111 nt
    Select Tool
    Polypeptide UniProtKB:A0A286YBU1 (1) 863 aa
    Sequence Information (all 35)
    ORTHOLOGY for agap1 ( Chr: 6 )
    CITATIONS (17)