Gene

agap1

ID
ZDB-GENE-130405-1
Name
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
Symbol
agap1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have several functions, including GTP binding activity; GTPase activator activity; and GTPase activity. Predicted to be involved in signal transduction. Predicted to localize to nucleus. Is expressed in cardiac ventricle. Orthologous to several human genes including AGAP1 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Singh et al., 2016
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from van Eyk et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With agap1 Human Ortholog
No data available
Associated With agap1 Via Experimental Models
Human Disease Fish Conditions Citations
cerebral palsy TU + MO1-agap1 standard conditions van Eyk et al., 2019
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001164 Arf GTPase activating protein
Domain IPR001849 Pleckstrin homology domain
Family IPR001806 Small GTPase
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036770 Ankyrin repeat-containing domain superfamily
Homologous_superfamily IPR037278 ARFGAP/RecO-like zinc finger
Homologous_superfamily IPR038508 ArfGAP domain superfamily
Repeat IPR002110 Ankyrin repeat
Domain Details Per Protein
Protein Length Ankyrin repeat Ankyrin repeat-containing domain superfamily ArfGAP domain superfamily ARFGAP/RecO-like zinc finger Arf GTPase activating protein PH-like domain superfamily Pleckstrin homology domain P-loop containing nucleoside triphosphate hydrolase Small GTPase
UniProtKB:A0A286YBU1 863
UniProtKB:E7FBZ7 858
UniProtKB:A0A0R4ITX1 828
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations