Gene

mrtfaa

ID
ZDB-GENE-121205-3
Name
myocardin related transcription factor Aa
Symbol
mrtfaa Nomenclature History
Previous Names
  • mkl1a
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and smooth muscle cell differentiation. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in acute megakaryocytic leukemia and immunodeficiency 66. Orthologous to human MRTFA (myocardin related transcription factor A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mrtfaa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency 66 Alliance ?Immunodeficiency 66 618847
Associated With mrtfaa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003034 SAP domain
Family IPR029992 MKL/myocardin-like protein 1
Family IPR043451 Myocardin-like
Homologous_superfamily IPR036361 SAP domain superfamily
Repeat IPR004018 RPEL repeat
Domain Details Per Protein
Protein Length MKL/myocardin-like protein 1 Myocardin-like RPEL repeat SAP domain SAP domain superfamily
UniProtKB:X1WDZ5 1118
UniProtKB:A0A2R8RI90 154
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations