ZFIN ID: ZDB-GENE-121205-3
Gene Name: myocardin related transcription factor Aa
Gene Symbol: mrtfaa    Nomenclature History

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Previous Name: mkl1a

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and smooth muscle cell differentiation. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in megakaryocytic leukemia. Orthologous to human MRTFA (myocardin related transcription factor A).
Genome Resources: Alliance (1),  Gene:797480 (1),  Ensembl(GRCz11):ENSDARG00000075867 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6887 Point Mutation Unknown Premature Stop ENU
sa10921 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20004 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25248 Point Mutation Unknown Splice Site ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mrtfaa HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    ?Immunodeficiency 66 618847
    DISEASE ASSOCIATED WITH mrtfaa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of transcription via serum response element binding (more)
    Cellular Component cytoplasm (more)
    Molecular Function actin binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mrtfaa-201 (1)    Ensembl 4584
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mrtfaa No data available
    MARKER RELATIONSHIPS
    mrtfaa Contained in: [BAC] CH73-165M10 (1), DKEY-68O6 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_009299400 (1)
    Genomic GenBank:BX569789 (1) 244662 nt Blast at MegaBLAST
    Polypeptide UniProtKB:X1WDZ5 (1) 1118 aa
    Sequence Information (all 21)
    ORTHOLOGY for mrtfaa ( Chr: 3 )
    CITATIONS (15)