ZFIN ID: ZDB-GENE-120215-253
Gene Name: CD109 molecule
Gene Symbol: cd109    Nomenclature History

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Previous Name: si:zfos-875e8.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have endopeptidase inhibitor activity. Predicted to localize to the extracellular space. Orthologous to human CD109 (CD109 molecule).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000060609 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa39309 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cd109 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cd109 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component extracellular region (more)
    Molecular Function endopeptidase inhibitor activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001599 Alpha-2-macroglobulin
    Domain IPR002890 Macroglobulin domain
    Homologous_superfamily IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
    Domain IPR011625 Alpha-2-macroglobulin, bait region domain
    Domain IPR011626 Alpha-macroglobulin-like, TED domain
    Homologous_superfamily IPR013783 Immunoglobulin-like fold
    Conserved_site IPR019742 Alpha-2-macroglobulin, conserved site
    Homologous_superfamily IPR036595 Alpha-macroglobulin, receptor-binding domain superfamily
    Domain IPR041555 Macroglobulin domain MG3
    Domain IPR041813 Alpha-2-macroglobulin, TED domain
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cd109-201 (1)    Ensembl 4036
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cd109 No data available
    MARKER RELATIONSHIPS
    cd109 Contained in: [Fosmid] CH1073-185L7 (1), ZFOS-875E8 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    Genomic GenBank:CU525921 (1) 38484 bp
    Select Tool
    Polypeptide UniProtKB:I3IS91 (1) 1337 aa
    Sequence Information (all 3)
    ORTHOLOGY for cd109 ( Chr: 20 )
    CITATIONS (10)