ZFIN ID: ZDB-GENE-110609-1
Gene Name: mesoderm posterior bb
Gene Symbol: mespbb    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in circulatory system development; regulation of skeletal muscle tissue development; and somitogenesis. Predicted to localize to nucleus. Is expressed in notochord outer sheath cell; paraxial mesoderm; post-vent region; and segmental plate. Orthologous to human MESP1 (mesoderm posterior bHLH transcription factor 1).
Genome Resources: Alliance (1),  Gene:100148845 (1),  Ensembl(GRCz11):ENSDARG00000097947 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
kt1006 Indel Unknown Unknown TALEN
kt1009 Small Deletion Unknown Unknown TALEN
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-mespbb N/A 1
MO2-mespbb N/A 1
MO3-mespbb N/A 1
TALEN1-mespbb 1
DISEASE ASSOCIATED WITH mespbb HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH mespbb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process determination of heart left/right asymmetry (more)
Molecular Function DNA-binding transcription factor activity (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA mespbb-201 (1)    Ensembl 860
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM mespbb
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(hsp70l:mespbb-MYC) hsp70l mespbbMYC Danio rerio 1 2
Tg(QUAS:mespbb-2A-EGFP) QUAS 2AEGFPmespbb Danio rerio 1 1
MARKER RELATIONSHIPS
mespbb Contained in: [BAC] DKEY-52P2 (order this), DKEY-167J6 (order this)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001265607 (1) 874 nt
Genomic GenBank:BX572619 (1) 171026 nt
Select Tool
Polypeptide UniProtKB:I2AVW0 (1) 244 aa
Sequence Information (all 7)
ORTHOLOGY for mespbb ( Chr: 25 )
CITATIONS (21)