ZFIN ID: ZDB-GENE-110407-10
Gene Name: junction plakoglobin b
Gene Symbol: jupb    Nomenclature History

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Previous Name: si:ch73-362f1.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have several functions, including alpha-catenin binding activity; cadherin binding activity; and transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to localize to adherens junction and catenin complex. Human ortholog(s) of this gene implicated in cardiomyopathy (multiple); palmoplantar keratosis (multiple); renal cell carcinoma; and reproductive organ cancer (multiple). Orthologous to human JUP (junction plakoglobin).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000059067 (2)
GENE EXPRESSION No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH jupb HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
arrhythmogenic right ventricular dysplasia 12 Alliance Arrhythmogenic right ventricular dysplasia 12 611528
Naxos disease Alliance Naxos disease 601214
DISEASE ASSOCIATED WITH jupb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cell adhesion (more)
Cellular Component adherens junction (more)
Molecular Function alpha-catenin binding (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA jupb-202 (1)    Ensembl 2313
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM jupb No data available
MARKER RELATIONSHIPS
jupb Contained in: [BAC] CH73-362F1 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
Genomic GenBank:FP236357 (1) 110439 nt
Select Tool
Polypeptide UniProtKB:F1QUV8 (1) 726 aa
Sequence Information (all 3)
ORTHOLOGY for jupb ( Chr: 19 )
CITATIONS (12)