Gene
fmn2a
- ID
- ZDB-GENE-101107-1
- Name
- formin 2a
- Symbol
- fmn2a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled acetylcholine receptor activity and G protein-coupled serotonin receptor activity. Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway and chemical synaptic transmission. Predicted to localize to dendrite; integral component of plasma membrane; and synapse. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human FMN2 (formin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 47 | Alliance | Intellectual developmental disorder, autosomal recessive 47 | 616193 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Formin, FH2 domain | Formin, FH2 domain superfamily | Formin homology family, Cappuccino subfamily |
|---|---|---|---|---|
|
UniProtKB:F1Q9W7
|
595 | |||
|
UniProtKB:X1WC43
|
1465 | |||
|
UniProtKB:A0A8M9P0I6
|
1445 | |||
|
UniProtKB:A0A8M9PV94
|
334 |
Interactions and Pathways
No data available
Plasmids
No data available