ZFIN ID: ZDB-GENE-100920-3
Gene Name: dynamin 1b
Gene Symbol: dnm1b    Nomenclature History

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Previous Name: si:ch73-310g9.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have GTPase activity and microtubule binding activity. Predicted to be involved in several processes, including membrane fusion; mitochondrial fission; and vesicle-mediated transport in synapse. Predicted to localize to several cellular components, including dendritic spine head; postsynaptic density; and postsynaptic endocytic zone membrane. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 31. Orthologous to human DNM1 (dynamin 1).
Genome Resources: Alliance (1),  Gene:100333543 (1),  Ensembl(GRCz11):ENSDARG00000009281 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa14849 Point Mutation Unknown Premature Stop ENU
sa17577 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18508 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dnm1b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    early infantile epileptic encephalopathy 31 Alliance Epileptic encephalopathy, early infantile, 31 616346
    DISEASE ASSOCIATED WITH dnm1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dynamin family protein polymerization involved in mitochondrial fission (more)
    Cellular Component axon (more)
    Molecular Function GTPase activity (more)
    GO Terms (all 25)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dnm1b-202 (1)    Ensembl 2925
    ncRNA dnm1b-002 (1) 774
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dnm1b No data available
    MARKER RELATIONSHIPS
    dnm1b Contained in: [BAC] CH73-274K23 (1), CH73-310G9 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001256818 (1)
    Genomic GenBank:CU856222 (1) 101502 nt
    Select Tool
    Polypeptide UniProtKB:E7FC95 (1) 858 aa
    Sequence Information (all 19)
    ORTHOLOGY for dnm1b ( Chr: 5 )
    CITATIONS (16)