Gene

aff4

ID

ZDB-GENE-100910-5

Name

AF4/FMR2 family, member 4

Symbol

aff4 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to be involved in regulation of gene expression. Predicted to localize to ELL-EAF complex. Orthologous to human AFF4 (AF4/FMR2 family member 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Diotel et al., 2015

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With aff4 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		CHOPS syndrome	616368

Associated With aff4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR043640	AF4/FMR2, C-terminal homology domain
Family	IPR007797	AF4/FMR2 family

Domain Details Per Protein

Protein	Length	AF4/FMR2, C-terminal homology domain	AF4/FMR2 family
UniProtKB:A0A8N7TEI3 InterPro	1078
UniProtKB:A0A8M2BL85 InterPro	1085
UniProtKB:I3ISK1 InterPro	1083

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	aff4-202 (1) Ensembl	Ensembl	524 nt	Select Tool ZFIN BLAST
mRNA	aff4-203 (1) Ensembl	Ensembl	3,441 nt	Select Tool ZFIN BLAST
ncRNA	aff4-003 (1) Ensembl	Ensembl	381 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations