Gene

kcnc3a

ID
ZDB-GENE-100901-1
Name
potassium voltage-gated channel, Shaw-related subfamily, member 3a
Symbol
kcnc3a Nomenclature History
Previous Names
  • kv3.3 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Exhibits voltage-gated potassium channel activity. Involved in motor neuron axon guidance. Predicted to localize to several cellular components, including dendrite membrane; neuronal cell body membrane; and voltage-gated potassium channel complex. Is expressed in Purkinje cell. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 13. Orthologous to human KCNC3 (potassium voltage-gated channel subfamily C member 3).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kcnc3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spinocerebellar ataxia type 13 Alliance Spinocerebellar ataxia 13 605259
Associated With kcnc3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000210 BTB/POZ domain
Domain IPR003131 Potassium channel tetramerisation-type BTB domain
Domain IPR005821 Ion transport domain
Domain IPR021105 Potassium channel, voltage dependent, Kv3, inactivation domain
Family IPR003968 Potassium channel, voltage dependent, Kv
Family IPR003974 Potassium channel, voltage dependent, Kv3
Family IPR028325 Voltage-gated potassium channel
Homologous_superfamily IPR011333 SKP1/BTB/POZ domain superfamily
Homologous_superfamily IPR027359 Voltage-dependent channel domain superfamily
Domain Details Per Protein
Protein Length BTB/POZ domain Ion transport domain Potassium channel tetramerisation-type BTB domain Potassium channel, voltage dependent, Kv Potassium channel, voltage dependent, Kv3 Potassium channel, voltage dependent, Kv3, inactivation domain SKP1/BTB/POZ domain superfamily Voltage-dependent channel domain superfamily Voltage-gated potassium channel
UniProtKB:F1Q4T8 626
UniProtKB:E1AZA5 659
UniProtKB:E1AZA4 642
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-kcnc3a Rabbit
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations