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General Information
ZIRC
ZFIN ID: ZDB-GENE-100727-1
Gene Name: CD40 ligand
Gene Symbol: cd40lg
Sequence Ontology ID : SO:0001217

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Attributions

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Previous Names: cd154 (1), TNFSF5 (1)

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(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits CD40 receptor binding activity. Involved in positive regulation of immunoglobulin production. Localizes to the external side of plasma membrane. Human ortholog(s) of this gene implicated in  ...
GENE EXPRESSION
All Expression Data: Fig. 9 from Gong et al., 2009
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa42412 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cd40lg HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    CD40 ligand deficiency Immunodeficiency, X-linked, with hyper-IgM 308230
    DISEASE ASSOCIATED WITH cd40lg VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of immunoglobulin production (more)
    Cellular Component external side of plasma membrane (more)
    Molecular Function CD40 receptor binding (more)
    GO Terms (all 9)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cd40lg-201 (1) 1791
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cd40lg No data available
    MARKER RELATIONSHIPS
    cd40lg Contained in: [BAC] CH211-127L15 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001144809 (1) 1804 bp
    Genomic GenBank:AL929434 (1) 178948 bp
    Select Tool
    Polypeptide UniProtKB:B8YI05 (1) 260 aa
    Sequence Clusters UniGene:117952 (1)
    Sequence Information (all 8)
    ORTHOLOGY for cd40lg ( Chr: 14 )
    CITATIONS (18)