Gene

afap1

ID
ZDB-GENE-100316-6
Name
actin filament associated protein 1
Symbol
afap1 Nomenclature History
Previous Names
  • im:7148276
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to be involved in regulation of cytoskeleton organization and regulation of signal transduction. Is expressed in brain. Human ortholog(s) of this gene implicated in open-angle glaucoma. Orthologous to human AFAP1 (actin filament associated protein 1).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With afap1 Human Ortholog
No data available
Associated With afap1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001849 Pleckstrin homology domain
Family IPR029907 Actin filament-associated protein 1
Family IPR030113 Actin-filament associated protein
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Protein Length Actin-filament associated protein Actin filament-associated protein 1 PH-like domain superfamily Pleckstrin homology domain
UniProtKB:A0A2R8QP26 213
UniProtKB:U3JAR6 806
UniProtKB:A0A2R8Q760 672
UniProtKB:A0A2R8RPV3 717
UniProtKB:E7F4D2 776
UniProtKB:A0A2R8Q5J8 289
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations