ZFIN ID: ZDB-GENE-100308-2
Gene Name: glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb
Gene Symbol: grin2cb    Nomenclature History

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Previous Name: NR2C.2 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have NMDA glutamate receptor activity and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential; glutamatergic synaptic transmission; and long-term synaptic potentiation. Predicted to localize to NMDA selective glutamate receptor complex and postsynaptic density membrane. Is expressed in brain. Orthologous to human GRIN2C (glutamate ionotropic receptor NMDA type subunit 2C).
Genome Resources: Alliance (1),  Gene:100333648 (1),  Ensembl(GRCz11):ENSDARG00000077560 (2)
GENE EXPRESSION
All Expression Data: Fig. 2 from Xie et al., 2017
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6265 Point Mutation Unknown Premature Stop ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH grin2cb HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH grin2cb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process ion transport (more)
Cellular Component cell junction (more)
Molecular Function ion channel activity (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA grin2cb-202 (1)    Ensembl 4940
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM grin2cb No data available
MARKER RELATIONSHIPS
grin2cb Contained in: [BAC] CH211-206J12 (1), DKEYP-101C8 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_009306796 (1)
Genomic RefSeq:NW_018394853 (1) Blast at MegaBLAST
Polypeptide UniProtKB:E7FGL8 (1) 1328 aa
Sequence Information (all 13)
ORTHOLOGY for grin2cb ( Chr: 12 )
CITATIONS (20)