Gene

grin2cb

ID
ZDB-GENE-100308-2
Name
glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb
Symbol
grin2cb Nomenclature History
Previous Names
  • NR2C.2 (1)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have NMDA glutamate receptor activity and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential; glutamatergic synaptic transmission; and long-term synaptic potentiation. Predicted to localize to NMDA selective glutamate receptor complex and postsynaptic density membrane. Is expressed in brain. Orthologous to human GRIN2C (glutamate ionotropic receptor NMDA type subunit 2C).
Genome Resources
Note
None
Expression
All Expression Data
Fig. 2 from Xie et al., 2017
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With grin2cb Human Ortholog
No data available
Associated With grin2cb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001320 Ionotropic glutamate receptor
Domain IPR001828 Receptor, ligand binding region
Domain IPR018884 Glutamate [NMDA] receptor, epsilon subunit, C-terminal
Domain IPR019594 Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
Family IPR001508 Ionotropic glutamate receptor, metazoa
Homologous_superfamily IPR028082 Periplasmic binding protein-like I
Domain Details Per Protein
Protein Length Glutamate [NMDA] receptor, epsilon subunit, C-terminal Ionotropic glutamate receptor Ionotropic glutamate receptor, L-glutamate and glycine-binding domain Ionotropic glutamate receptor, metazoa Periplasmic binding protein-like I Receptor, ligand binding region
UniProtKB:E7FGL8 1328
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations