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ZIRC
ZFIN ID: ZDB-GENE-100302-1
Gene Name: von Willebrand factor A domain containing 2
Gene Symbol: vwa2    Nomenclature History

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Previous Name: AMACO (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity. Involved in epithelial structure maintenance. Predicted to localize to the collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, including fin; median fin fold; myoseptum; nervous system; and somite. Orthologous to human VWA2 (von Willebrand factor A domain containing 2).
Genome Resources: Alliance (1),  Gene:567428 (1),  Ensembl(GRCz11):ENSDARG00000075441 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15844 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18645 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22126 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22127 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-vwa2 N/A 1
    MO2-vwa2 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH vwa2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH vwa2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process epithelial structure maintenance (more)
    Cellular Component basement membrane (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 7)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA vwa2-201 (1)    Ensembl 2470
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-vwa2 polyclonal Rabbit IHC, WB 2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM vwa2 No data available
    MARKER RELATIONSHIPS
    vwa2 Contained in: [BAC] CH211-225B10 (1) (order this), DKEYP-84E12 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_690723 (1) 2388 bp
    Genomic GenBank:BX465198 (1) 194152 bp
    Select Tool
    Polypeptide UniProtKB:U3JA51 (1) 795 aa
    Sequence Clusters UniGene:158880 (1)
    Sequence Information (all 18)
    ORTHOLOGY for vwa2 ( Chr: 12 )
    CITATIONS (15)