Gene
pigo
- ID
- ZDB-GENE-091204-80
- Name
- phosphatidylinositol glycan anchor biosynthesis, class O
- Symbol
- pigo Nomenclature History
- Previous Names
-
- si:dkey-200l5.3
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable mannose-ethanolamine phosphotransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hyperphosphatasia with impaired intellectual development syndrome 2. Orthologous to human PIGO (phosphatidylinositol glycan anchor biosynthesis class O).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hyperphosphatasia with impaired intellectual development syndrome 2 | Alliance | Hyperphosphatasia with impaired intellectual development syndrome 2 | 614749 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR037675 | GPI ethanolamine phosphate transferase 3, N-terminal |
| Family | IPR002591 | Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase |
| Family | IPR039524 | GPI ethanolamine phosphate transferase 3 |
| Homologous_superfamily | IPR017850 | Alkaline-phosphatase-like, core domain superfamily |
Domain Details Per Protein
| Protein | Length | Alkaline-phosphatase-like, core domain superfamily | GPI ethanolamine phosphate transferase 3 | GPI ethanolamine phosphate transferase 3, N-terminal | Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase |
|---|---|---|---|---|---|
|
UniProtKB:E9QI13
|
1075 |
Interactions and Pathways
No data available
Plasmids
No data available