Gene

pdk1

ID
ZDB-GENE-091204-402
Name
pyruvate dehydrogenase kinase, isozyme 1
Symbol
pdk1 Nomenclature History
Previous Names
  • si:zfos-979f1.3
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to enable pyruvate dehydrogenase (acetyl-transferring) kinase activity. Predicted to be involved in protein phosphorylation and regulation of glucose metabolic process. Predicted to act upstream of or within phosphorylation. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Orthologous to human PDK1 (pyruvate dehydrogenase kinase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pdk1 Human Ortholog
No data available
Associated With pdk1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003594 Histidine kinase/HSP90-like ATPase
Domain IPR005467 Histidine kinase domain
Domain IPR018955 Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal
Family IPR039028 PDK/BCKDK protein kinase
Homologous_superfamily IPR036784 Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily
Homologous_superfamily IPR036890 Histidine kinase/HSP90-like ATPase superfamily
Domain Details Per Protein
Protein Length Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal Histidine kinase domain Histidine kinase/HSP90-like ATPase Histidine kinase/HSP90-like ATPase superfamily PDK/BCKDK protein kinase
UniProtKB:E7F3U3 405
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations