ZFIN ID: ZDB-GENE-091204-402
Gene Name: pyruvate dehydrogenase kinase, isozyme 1
Gene Symbol: pdk1    Nomenclature History

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Previous Name: si:zfos-979f1.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in glucose homeostasis and negative regulation of pyruvate dehydrogenase activity. Predicted to localize to mitochondrion. Orthologous to human PDK1 (pyruvate dehydrogenase kinase 1).
Genome Resources: Alliance (1),  Gene:555840 (1),  Ensembl(GRCz11):ENSDARG00000013128 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa21421 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-pdk1 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pdk1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pdk1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphorylation (more)
    Cellular Component mitochondrial matrix (more)
    Molecular Function ATP binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pdk1-201 (1)    Ensembl 1684
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pdk1 No data available
    MARKER RELATIONSHIPS
    pdk1 Contained in: [Fosmid] ZFOS-979F1 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_678484 (1)
    Genomic GenBank:FP236594 (1) 45097 nt
    Select Tool
    Polypeptide UniProtKB:E7F3U3 (1) 405 aa
    Sequence Information (all 7)
    ORTHOLOGY for pdk1 ( Chr: 9 )
    CITATIONS (24)