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ZIRC
ZFIN ID: ZDB-GENE-091118-62
Gene Name: solute carrier family 22 member 21
Gene Symbol: slc22a21    Nomenclature History

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Attributions

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Previous Names: C2 (1), ergothioneine transporter (1), ETTzf (1), si:ch1073-409b12.4

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Exhibits amino-acid betaine transmembrane transporter activity. Involved in amino-acid betaine transport. Predicted to localize to the integral component of membrane. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Is expressed in brain; eye; integument; intestine; and kidney. Orthologous to human SLC22A4 (solute carrier family 22 member 4).
Genome Resources: Alliance (1),  Gene:799908 (1),  Ensembl(GRCz11):ENSDARG00000094112 (2)
GENE EXPRESSION
All Expression Data: Fig. 2 from Pfeiffer et al., 2015
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ipk1Tg Transgenic Insertion Unknown Unknown DNA
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH slc22a21 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH slc22a21 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process amino-acid betaine transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function amino-acid betaine transmembrane transporter activity (more)
    GO Terms (all 8)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA slc22a21-201 (1)    Ensembl 1045
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slc22a21 No data available
    MARKER RELATIONSHIPS
    slc22a21 Contained in: [Fosmid] CH1073-409B12 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001308558 (1)
    Genomic GenBank:CU469525 (1) 36295 bp
    Select Tool
    Polypeptide UniProtKB:A0A0E4G213 (1) 546 aa
    Sequence Information (all 12)
    ORTHOLOGY for slc22a21 ( Chr: 21 )
    CITATIONS (15)