Gene

slc4a4b

ID
ZDB-GENE-091030-1
Name
solute carrier family 4 member 4b
Symbol
slc4a4b Nomenclature History
Previous Names
  • nbce1 (1)
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have sodium:bicarbonate symporter activity. Predicted to be involved in bicarbonate transport and regulation of intracellular pH. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in renal tubular acidosis. Is expressed in several structures, including NCC ionocyte; ball; gill; nervous system; and pleuroperitoneal region. Orthologous to human SLC4A4 (solute carrier family 4 member 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc4a4b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Renal tubular acidosis, proximal, with ocular abnormalities 604278
Associated With slc4a4b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011531 Bicarbonate transporter, C-terminal
Domain IPR013769 Band 3 cytoplasmic domain
Family IPR003020 Bicarbonate transporter, eukaryotic
Family IPR003024 Sodium bicarbonate cotransporter
Homologous_superfamily IPR016152 Phosphotransferase/anion transporter
Domain Details Per Protein
Protein Length Band 3 cytoplasmic domain Bicarbonate transporter, C-terminal Bicarbonate transporter, eukaryotic Phosphotransferase/anion transporter Sodium bicarbonate cotransporter
UniProtKB:A0A0R4IUL4 1113
UniProtKB:F1QD14 1090
UniProtKB:A9XST2 973
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations