ZFIN ID: ZDB-GENE-090629-1
Gene Name: endothelial cell adhesion molecule a
Gene Symbol: esama    Nomenclature History

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Previous Names: esam, zESAMa (1), sc:d0254

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Involved in cell adhesion involved in sprouting angiogenesis and platelet aggregation. Predicted to localize to integral component of membrane. Is expressed in several structures, including angioblastic mesenchymal cell; cardiovascular system; epiphysis; otic vesicle; and ventral mesoderm. Orthologous to human ESAM (endothelial cell adhesion molecule).
Genome Resources: Alliance (1),  Gene:799432 (1),  Ensembl(GRCz11):ENSDARG00000077039 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la017512Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa8787 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21761 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • ubs19 Small Deletion Exon 2 Premature Stop TALEN
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-esama N/A 1
    MO2-esama N/A 1
    TALEN1-esama 1
    DISEASE ASSOCIATED WITH esama HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH esama VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell adhesion involved in sprouting angiogenesis (more)
    Cellular Component integral component of membrane (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA esama-201 (1)    Ensembl 1813
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-esama polyclonal Rabbit IHC 2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM esama No data available
    MARKER RELATIONSHIPS
    esama Contained in: [BAC] CH211-80M8 (1), DKEY-91C10 (order this)
    esama Encodes: [EST] cssl:d0254 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001115066 (1) 1574 nt
    Genomic GenBank:BX571852 (1) 178333 nt
    Select Tool
    Polypeptide UniProtKB:B0CLV1 (1) 428 aa
    Sequence Information (all 15)
    ORTHOLOGY for esama ( Chr: 10 )
    CITATIONS (29)