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General Information
ZIRC
ZFIN ID: ZDB-GENE-090507-4
Gene Name: tubulin, alpha 1a
Gene Symbol: tuba1a
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: tuba1l2, wu:fb37a10

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have GTP binding activity. Involved in negative regulation of apoptotic process and optic nerve formation. Predicted to localize to the cytoplasm and microtubule. Human ortholog(s) of  ...
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:85639]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
DISEASE ASSOCIATED WITH tuba1a HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
lissencephaly Lissencephaly 3 611603
DISEASE ASSOCIATED WITH tuba1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of apoptotic process (more)
Cellular Component cytoplasm (more)
Molecular Function GTPase activity (more)
GO Terms (all 12)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA tuba1a-201 (1) 1537
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIESNo data available
PLASMIDSNo data available
CONSTRUCTS WITH SEQUENCES FROM tuba1a No data available
MARKER RELATIONSHIPS
tuba1aContained in: [BAC] DKEY-18F23 (1) (order this)
tuba1aContains: [SNP] rs3729281, rs3729282, rs3729283, rs3729284
tuba1aEncodes: [EST] fb37a10 (1)
[cDNA] MGC:85639 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001190982 (1) 1600bp
Genomic GenBank:BX465853 (1) 220945bp Blast at MegaBLAST
Polypeptide UniProtKB:Q6NWK7 (1) 451aa
Sequence Clusters UniGene:11310 (1)
Sequence Information (all 11)
ORTHOLOGY for tuba1a (Chr: 23)
CITATIONS (26)