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ZIRC
ZFIN ID: ZDB-GENE-090507-2
Gene Name: toll-like receptor 4a, like
Gene Symbol: tlr4al    Nomenclature History

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Previous Name: tlr4ba (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to be involved in inflammatory response and toll-like receptor signaling pathway. Predicted to localize to the integral component of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); diabetes mellitus (multiple); eye disease (multiple); lung disease (multiple); and vasculitis (multiple). Orthologous to human TLR4 (toll like receptor 4).
Genome Resources: Alliance (1),  Gene:795671 (1),  Ensembl(GRCz11):ENSDARG00000075671 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa11530 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-tlr4al N/A 1
    MO2-tlr4al N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tlr4al HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tlr4al VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process signal transduction (more)
    Cellular Component integral component of membrane (more)
    GO Terms (all 6)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tlr4al-201 (1)    Ensembl 2473
    Browsers: UCSCEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tlr4al No data available
    MARKER RELATIONSHIPS
    tlr4al Contained in: [BAC] CH211-198A12 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001328605 (1)
    Genomic GenBank:BX908770 (1) 126240 bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8QL77 (1) 818 aa
    Sequence Information (all 8)
    ORTHOLOGY for tlr4al ( Chr: 13 )
    CITATIONS (20)