Gene

chrm1a

ID
ZDB-GENE-090410-9
Name
cholinergic receptor, muscarinic 1a
Symbol
chrm1a Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have G protein-coupled acetylcholine receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to localize to cell junction; integral component of plasma membrane; and postsynaptic membrane. Human ortholog(s) of this gene implicated in Lambert-Eaton myasthenic syndrome; asthma; and myasthenia gravis. Is expressed in eye. Orthologous to human CHRM1 (cholinergic receptor muscarinic 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Nuckels et al., 2011
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With chrm1a Human Ortholog
No data available
Associated With chrm1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR000995 Muscarinic acetylcholine receptor family
Domain Details Per Protein
Protein Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like Muscarinic acetylcholine receptor family
UniProtKB:A0A8M1Q6V1 442
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA chrm1a-202 (1) Havana 1422 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations