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General Information
ZIRC
ZFIN ID: ZDB-GENE-090313-95
Gene Name: CD40 molecule, TNF receptor superfamily member 5
Gene Symbol: cd40
Sequence Ontology ID : SO:0000704

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Previous Names: si:ch211-231h20.3 (1), tnfsrf5 (1)

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits CD154 receptor binding activity; involved in TRIF-dependent toll-like receptor signaling pathway; localizes to the external side of plasma membrane; orthologous to human CD40 (CD40 molecule).
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH cd40 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
CD40 deficiency Immunodeficiency with hyper-IgM, type 3 606843
DISEASE ASSOCIATED WITH cd40 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process TRIF-dependent toll-like receptor signaling pathway (more)
Cellular Component external side of plasma membrane (more)
Molecular Function CD154 receptor binding (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001368 (1)
  • InterPro:IPR034053 (1)
  • PROSITE:PS50050 (1)
  • Pfam:PF00020 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cd40-201 (1) 1175
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cd40 No data available
    MARKER RELATIONSHIPS
    cd40Contained in: [BAC] CH211-231H20 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001145246 (1) 1617bp
    Genomic GenBank:CR381544 (1) 146827bp
    Select Tool
    Polypeptide UniProtKB:B8X730 (1) 286aa
    Sequence Clusters UniGene:92473 (1)
    Sequence Information (all 8)
    ORTHOLOGY for cd40 (Chr: 23)
    CITATIONS (25)