Gene

fbxw7

ID
ZDB-GENE-090313-79
Name
F-box and WD repeat domain containing 7
Symbol
fbxw7 Nomenclature History
Previous Names
  • si:ch211-208n2.1
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Acts upstream of or within angiogenesis; negative regulation of myelination; and regulation of signal transduction. Is expressed in glioblast (sensu Vertebrata); neural tube; neuroblast (sensu Vertebrata); spinal cord; and trunk. Orthologous to human FBXW7 (F-box and WD repeat domain containing 7).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
13 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fbxw7 Human Ortholog
No data available
Associated With fbxw7 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR001810 F-box domain
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036047 F-box-like domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Repeat IPR020472 G-protein beta WD-40 repeat
Domain Details Per Protein
Protein Length F-box domain F-box-like domain superfamily G-protein beta WD-40 repeat WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:B7ZDC8
UniProtKB:B8A474
UniProtKB:F1RCB5
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-fbxw7 polyclonal Rabbit
  • WB
Millipore
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations