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General Information
ZIRC
ZFIN ID: ZDB-GENE-090313-71
Gene Name: DNA replication helicase/nuclease 2
Gene Symbol: dna2
Sequence Ontology ID : SO:0001217

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Previous Name: si:ch211-1n9.7 (1)

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have 5'-flap endonuclease activity and RNA binding activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis and replication fork reversal. Predicted to localize  ...
GENE EXPRESSION
All Expression Data: Fig. S2 from Yang et al., 2013
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH dna2 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Seckel syndrome 8 ?Seckel syndrome 8 615807
Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 6 615156
DISEASE ASSOCIATED WITH dna2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process DNA metabolic process (more)
Cellular Component cytoplasm (more)
Molecular Function 5'-flap endonuclease activity (more)
GO Terms (all 10)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA dna2-202 (1) 4753
 Withdrawn Transcriptsextinct
GENE PRODUCT DESCRIPTION No description available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM dna2 No data available
MARKER RELATIONSHIPS
dna2 Contained in: [BAC] CH211-1N9 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:XM_682882 (1) 4510 bp
Genomic GenBank:BX530068 (1) 185626 bp
Select Tool
Polypeptide UniProtKB:F1Q892 (1) 1378 aa
Sequence Clusters UniGene:156870 (1)
Sequence Information (all 23)
ORTHOLOGY for dna2 ( Chr: 13 )
CITATIONS (17)