Gene

plcl1

ID
ZDB-GENE-090313-194
Name
phospholipase C like 1
Symbol
plcl1 Nomenclature History
Previous Names
  • si:dkey-15m21.1
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have GABA receptor binding activity; inositol 1,4,5 trisphosphate binding activity; and phosphatidylinositol phospholipase C activity. Predicted to be involved in inositol trisphosphate biosynthetic process; phosphatidylinositol-mediated signaling; and release of sequestered calcium ion into cytosol. Is expressed in hindbrain; lateral line nerve; and spinal cord. Orthologous to human PLCL1 (phospholipase C like 1 (inactive)).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from Takada et al., 2010
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. S4 from Thyme et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With plcl1 Human Ortholog
No data available
Associated With plcl1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000008 C2 domain
Domain IPR000909 Phosphatidylinositol-specific phospholipase C, X domain
Domain IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR015359 Phosphoinositide-specific phospholipase C, EF-hand-like domain
Family IPR001192 Phosphoinositide phospholipase C family
Family IPR042124 Inactive phospholipase C-like protein 1
Homologous_superfamily IPR011992 EF-hand domain pair
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
Homologous_superfamily IPR035892 C2 domain superfamily
Domain Details Per Protein
Protein Length C2 domain C2 domain superfamily EF-hand domain pair Inactive phospholipase C-like protein 1 PH-like domain superfamily Phosphatidylinositol-specific phospholipase C, X domain Phosphoinositide phospholipase C family Phosphoinositide-specific phospholipase C, EF-hand-like domain Phospholipase C, phosphatidylinositol-specific, Y domain PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily Pleckstrin homology domain
UniProtKB:A0A2R8RJ32 1030
UniProtKB:A0A2R8QV76 1009
UniProtKB:A0A2R8QSM3 923
UniProtKB:F1Q7A3 1125
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations