ZFIN ID: ZDB-GENE-090313-160
Gene Name: guanylate cyclase 1 soluble subunit beta 1
Gene Symbol: gucy1b1    Nomenclature History

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Previous Names: gucy1b3, si:ch73-34b5.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have guanylate cyclase activity; heme binding activity; and nucleotide binding activity. Predicted to be involved in cGMP-mediated signaling and trans-synaptic signaling by nitric oxide, modulating synaptic transmission. Predicted to localize to presynaptic active zone. Orthologous to human GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1).
Genome Resources: Alliance (1),  Gene:100150304 (1), 
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16873 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko496a Insertion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • zko496b Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-gucy1b1 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gucy1b1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gucy1b1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cGMP biosynthetic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function GTP binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gucy1b1-201 (1)    Ensembl 2122
    ncRNA gucy1b3-002 (1)    Ensembl 699
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gucy1b1 No data available
    MARKER RELATIONSHIPS
    gucy1b1 Contained in: [BAC] CH73-34B5 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001251945 (1)
    Genomic GenBank:CU571168 (1) 111328 nt
    Select Tool
    Polypeptide UniProtKB:F1QNR4 (1) 608 aa
    Sequence Information (all 14)
    ORTHOLOGY for gucy1b1 ( Chr: 1 )
    CITATIONS (19)