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Gene

gucy1b1

ID
ZDB-GENE-090313-160
Name
guanylate cyclase 1 soluble subunit beta 1
Symbol
gucy1b1 Nomenclature History
Previous Names
  • gucy1b3
  • si:ch73-34b5.3
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable GTP binding activity; guanylate cyclase activity; and heme binding activity. Predicted to be involved in cGMP-mediated signaling and trans-synaptic signaling by nitric oxide, modulating synaptic transmission. Predicted to act upstream of or within cGMP biosynthetic process and intracellular signal transduction. Predicted to be located in cytoplasm. Predicted to be active in presynaptic active zone. Orthologous to human GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gucy1b1 Human Ortholog
No data available
Associated With gucy1b1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved site
Domain IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase
Domain IPR011644 Heme NO-binding
Domain IPR011645 Haem NO binding associated
Homologous_superfamily IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily
Homologous_superfamily IPR029787 Nucleotide cyclase
Homologous_superfamily IPR038158 H-NOX domain superfamily
Homologous_superfamily IPR042463 Haem NO binding associated domain superfamily
Domain Details Per Protein
Protein Length Adenylyl cyclase class-3/4/guanylyl cyclase Adenylyl cyclase class-4/guanylyl cyclase, conserved site Haem NO binding associated Haem NO binding associated domain superfamily Heme NO-binding H-NOX domain superfamily NO signalling/Golgi transport ligand-binding domain superfamily Nucleotide cyclase
UniProtKB:F1QNR4 608
UniProtKB:A0A2R8QBS1 602
UniProtKB:F6M8W7 118
UniProtKB:D1LXJ3 111
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations