ZFIN ID: ZDB-GENE-090313-152
Gene Name: adhesion G protein-coupled receptor E10
Gene Symbol: adgre10    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: emrl10 (1), si:ch73-341p18.7

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to localize to the integral component of plasma membrane. Human ortholog(s) of this gene implicated in vibratory urticaria. Is expressed in kidney; liver; muscle; ovary; and testis. Orthologous to human ADGRE1 (adhesion G protein-coupled receptor E1); ADGRE2 (adhesion G protein-coupled receptor E2); and ADGRE3 (adhesion G protein-coupled receptor E3).
Genome Resources: Alliance (1),  Gene:569655 (1),  Ensembl(GRCz11):ENSDARG00000075855 (2)
GENE EXPRESSION
All Expression Data: Fig. 6 from Harty et al., 2015
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6607 Point Mutation Unknown Splice Site ENU
sa7415 Point Mutation Unknown Missense ENU
zko1136a Indel Unknown Unknown CRISPR
zko1136b Indel Unknown Unknown CRISPR
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-adgre10 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH adgre10 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH adgre10 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cell surface receptor signaling pathway (more)
Cellular Component integral component of membrane (more)
Molecular Function G protein-coupled receptor activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR000203 GPS motif
Family IPR000832 GPCR, family 2, secretin-like
Family IPR001740 GPCR family 2, EMR1-like receptor
Domain IPR017981 GPCR, family 2-like
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA adgre10-201 (1)    Ensembl 3625
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM adgre10 No data available
MARKER RELATIONSHIPS
adgre10 Contained in: [BAC] CH73-341P18 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:XM_021478071 (1)
Genomic GenBank:CU571167 (1) 122272 bp
Select Tool
Polypeptide UniProtKB:F1QAE5 (1) 690 aa
Sequence Information (all 6)
ORTHOLOGY for adgre10 ( Chr: 1 )
CITATIONS (16)