Gene

dok7

ID
ZDB-GENE-090312-103
Name
docking protein 7
Symbol
dok7 Nomenclature History
Previous Names
  • si:ch211-164d19.2
  • si:dkey-180b4.3
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have protein kinase binding activity. Involved in skeletal muscle fiber development; synapse organization; and thigmotaxis. Is expressed in post-vent region and tail bud. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 10 and fetal akinesia deformation sequence syndrome 3. Orthologous to human DOK7 (docking protein 7).
Genome Resources
Note
None
Expression
All Expression Data
Fig. 2 from Müller et al., 2010
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Müller et al., 2010
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dok7 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital myasthenic syndrome 10 Alliance Myasthenic syndrome, congenital, 10 254300
fetal akinesia deformation sequence syndrome 3 Alliance Fetal akinesia deformation sequence 3 618389
Associated With dok7 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001849 Pleckstrin homology domain
Domain IPR002404 IRS-type PTB domain
Domain IPR037748 Dok-7, PTB domain
Family IPR037746 Protein Dok-7
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Protein Length Dok-7, PTB domain IRS-type PTB domain PH-like domain superfamily Pleckstrin homology domain Protein Dok-7
UniProtKB:F1R1E6 480
UniProtKB:F6P2Z4 695
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations