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General Information
ZIRC
ZFIN ID: ZDB-GENE-090311-53
Gene Name: caspase b, like
Gene Symbol: caspbl    Nomenclature History

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Attributions

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Previous Names: casp19b (1), si:ch211-15j1.6

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have cysteine-type endopeptidase activity involved in apoptotic signaling pathway. Predicted to be involved in activation of cysteine-type endopeptidase activity involved in apoptotic process and apoptotic process. Predicted to localize to the cytoplasm. Orthologous to human CASP1 (caspase 1) and CASP4 (caspase 4).
Genome Resources: Alliance (1),  Gene:566185 (1),  Ensembl(GRCz11):ENSDARG00000094433 (2)
GENE EXPRESSION
All Expression Data: Fig. 4 from Spead et al., 2018
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Larval:Day 4 (96.0h-120.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR5-caspb,caspbl
1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH caspbl HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH caspbl VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Cellular Component cytoplasm (more)
Molecular Function cysteine-type endopeptidase activity (more)
GO Terms (all 10)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA caspbl-202 (1)    Ensembl 1993
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM caspbl No data available
MARKER RELATIONSHIPS
caspbl Contained in: [BAC] CH211-15J1 (1) (order this), CH211-114L13 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001145592 (1)
Genomic GenBank:BX469930 (1) 183380 bp
Select Tool
Polypeptide UniProtKB:B8A526 (1) 409 aa
Sequence Clusters UniGene:40733 (1)
Sequence Information (all 12)
ORTHOLOGY for caspbl ( Chr: 1 )
CITATIONS (15)