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General Information
ZIRC
ZFIN ID: ZDB-GENE-090212-1
Gene Name: alpha-2-macroglobulin-like
Gene Symbol: a2ml
Sequence Ontology ID : SO:0001217

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(Including Attributions)
Location: Chr: 15 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have endopeptidase inhibitor activity. Involved in liver development. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in background diabetic  ...
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6372 Point Mutation Unknown Premature Stop ENU
sa10524 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12900 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH a2ml HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH a2ml VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process liver development (more)
    Cellular Component extracellular region (more)
    Molecular Function endopeptidase inhibitor activity (more)
    GO Terms (all 4)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA a2ml-201 (1) 4537
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM a2ml No data available
    MARKER RELATIONSHIPS
    a2ml Contained in: [BAC] DKEY-52D15 (1) (order this)
    a2ml Encodes: [EST] fc90g08
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001139479 (1) 4566 bp
    Genomic GenBank:CR626907 (1) 206211 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F6NTZ9 (1) 1448 aa
    Sequence Clusters UniGene:75455 (1)
    Sequence Information (all 22)
    ORTHOLOGY for a2ml ( Chr: 15 )
    CITATIONS (24)