Gene

a2ml

ID
ZDB-GENE-090212-1
Name
alpha-2-macroglobulin-like
Symbol
a2ml Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have serine-type endopeptidase inhibitor activity. Involved in liver development. Predicted to localize to extracellular space. Is expressed in gut; liver; yolk; and yolk syncytial layer.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With a2ml Human Ortholog
No data available
Associated With a2ml Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019742 Alpha-2-macroglobulin, conserved site
Domain IPR001599 Alpha-2-macroglobulin
Domain IPR002890 Macroglobulin domain
Domain IPR009048 Alpha-macroglobulin, receptor-binding
Domain IPR011625 Alpha-2-macroglobulin, bait region domain
Domain IPR011626 Alpha-macroglobulin-like, TED domain
Domain IPR040839 Macroglobulin domain MG4
Domain IPR041555 Macroglobulin domain MG3
Domain IPR041813 Alpha-2-macroglobulin, TED domain
Homologous_superfamily IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR014756 Immunoglobulin E-set
Homologous_superfamily IPR036595 Alpha-macroglobulin, receptor-binding domain superfamily
Domain Details Per Protein
Protein Length Alpha-2-macroglobulin Alpha-2-macroglobulin, bait region domain Alpha-2-macroglobulin, conserved site Alpha-2-macroglobulin, TED domain Alpha-macroglobulin-like, TED domain Alpha-macroglobulin, receptor-binding Alpha-macroglobulin, receptor-binding domain superfamily Immunoglobulin E-set Immunoglobulin-like fold Macroglobulin domain Macroglobulin domain MG3 Macroglobulin domain MG4 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
UniProtKB:A0JMP8 1444
UniProtKB:B8QSI4 1442
UniProtKB:F6NTZ9 1448
UniProtKB:A8KAZ5 580
UniProtKB:A0A0R4IDD1 1442
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations