Gene
sox6
- ID
- ZDB-GENE-081120-6
- Name
- SRY-box transcription factor 6
- Symbol
- sox6 Nomenclature History
- Previous Names
-
- sox6b (1)
- fc35a10
- fc50e03
- wu:fc35a10
- wu:fc50e03
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within adipose tissue development; muscle cell fate specification; and skeletal muscle tissue development. Predicted to be active in nucleus. Is expressed in fast muscle cell; myotome; pharyngeal arch 3-7; and somite. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human SOX6 (SRY-box transcription factor 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
-
- GEO (1) Expression Atlas (1) UCSC scRNA-seq (1)
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 10 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Tolchin-Le Caignec syndrome | 618971 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | High mobility group box domain | High mobility group box domain superfamily | Transcription factor SOX-6 |
|---|---|---|---|---|
|
UniProtKB:B2CNY6
|
||||
|
UniProtKB:F8W2H3
|
768 | |||
|
UniProtKB:G3KFL6
|
80 | |||
|
UniProtKB:A0A2R8RIJ5
|
784 | |||
|
UniProtKB:Q2MGT7
|
686 | |||
|
UniProtKB:A0A1D5NSY8
|
121 | |||
|
UniProtKB:A0A2R8QLT0
|
816 | |||
|
UniProtKB:A0A1D5NSK3
|
785 | |||
|
UniProtKB:G3KFL7
|
97 |
Interactions and Pathways
No data available
Plasmids
No data available