Gene

ubr2

ID
ZDB-GENE-081107-29
Name
ubiquitin protein ligase E3 component n-recognin 2
Symbol
ubr2 Nomenclature History
Previous Names
  • si:ch211-239i4.2
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have ubiquitin protein ligase activity. Predicted to be involved in chromatin silencing; histone H2A ubiquitination; and ubiquitin-dependent protein catabolic process via the N-end rule pathway. Predicted to localize to cytoplasm and ubiquitin ligase complex. Is expressed in female organism. Orthologous to human UBR2 (ubiquitin protein ligase E3 component n-recognin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Newman et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ubr2 Human Ortholog
No data available
Associated With ubr2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003126 Zinc finger, UBR-type
Domain IPR003769 Adaptor protein ClpS, core
Domain IPR044046 E3 ubiquitin-protein ligase UBR-like, C-terminal
Domain IPR047508 E3 ubiquitin-protein ligase UBR2, UBR-box
Family IPR039164 E3 ubiquitin-protein ligase UBR1-like
Homologous_superfamily IPR014719 Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Homologous_superfamily IPR042065 E3 ubiquitin-protein ligase ELL-like
Domain Details Per Protein
Protein Length Adaptor protein ClpS, core E3 ubiquitin-protein ligase ELL-like E3 ubiquitin-protein ligase UBR1-like E3 ubiquitin-protein ligase UBR2, UBR-box E3 ubiquitin-protein ligase UBR-like, C-terminal Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like Winged helix DNA-binding domain superfamily Zinc finger, UBR-type
UniProtKB:A0A8M2B2U0 1756
UniProtKB:A0A8M9PB10 946
UniProtKB:A0A8M6Z2H4 1770
UniProtKB:A0A8M2B2K6 1757
UniProtKB:A0A8M9PML5 546
UniProtKB:A0A8M1QLF4 1756
UniProtKB:A0A8M6Z1W9 1771
UniProtKB:A0A8M6Z9B0 1771
UniProtKB:A0A8M6Z417 1371
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA ubr2-201 (1) Ensembl 5142 nt
mRNA ubr2-202 (1) Havana 6069 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations