Gene
ubr2
- ID
- ZDB-GENE-081107-29
- Name
- ubiquitin protein ligase E3 component n-recognin 2
- Symbol
- ubr2 Nomenclature History
- Previous Names
-
- si:ch211-239i4.2
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have ubiquitin protein ligase activity. Predicted to be involved in chromatin silencing; histone H2A ubiquitination; and ubiquitin-dependent protein catabolic process via the N-end rule pathway. Predicted to localize to cytoplasm and ubiquitin ligase complex. Is expressed in female organism. Orthologous to human UBR2 (ubiquitin protein ligase E3 component n-recognin 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Newman et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR003126 | Zinc finger, UBR-type |
Domain | IPR003769 | Adaptor protein ClpS, core |
Domain | IPR044046 | E3 ubiquitin-protein ligase UBR-like, C-terminal |
Domain | IPR047508 | E3 ubiquitin-protein ligase UBR2, UBR-box |
Family | IPR039164 | E3 ubiquitin-protein ligase UBR1-like |
Homologous_superfamily | IPR014719 | Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like |
Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Homologous_superfamily | IPR042065 | E3 ubiquitin-protein ligase ELL-like |
Domain Details Per Protein
Protein | Length | Adaptor protein ClpS, core | E3 ubiquitin-protein ligase ELL-like | E3 ubiquitin-protein ligase UBR1-like | E3 ubiquitin-protein ligase UBR2, UBR-box | E3 ubiquitin-protein ligase UBR-like, C-terminal | Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like | Winged helix DNA-binding domain superfamily | Zinc finger, UBR-type |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M2B2U0
|
1756 | ||||||||
UniProtKB:A0A8M9PB10
|
946 | ||||||||
UniProtKB:A0A8M6Z2H4
|
1770 | ||||||||
UniProtKB:A0A8M2B2K6
|
1757 | ||||||||
UniProtKB:A0A8M9PML5
|
546 | ||||||||
UniProtKB:A0A8M1QLF4
|
1756 | ||||||||
UniProtKB:A0A8M6Z1W9
|
1771 | ||||||||
UniProtKB:A0A8M6Z9B0
|
1771 | ||||||||
UniProtKB:A0A8M6Z417
|
1371 |
Interactions and Pathways
No data available
Plasmids
No data available