ZFIN ID: ZDB-GENE-081105-95
Gene Name: G protein-coupled receptor kinase 5 like
Gene Symbol: grk5l    Nomenclature History

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Previous Name: si:dkey-220o5.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and G protein-coupled receptor kinase activity. Involved in determination of left/right symmetry; negative regulation of TOR signaling; and regulation of cilium assembly. Localizes to plasma membrane. Is expressed in several structures, including notochord; otic placode; pronephros; spinal cord; and tail bud. Orthologous to human GRK5 (G protein-coupled receptor kinase 5).
Genome Resources: Alliance (1),  Gene:567452 (1),  Ensembl(GRCz11):ENSDARG00000078815 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026584Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la026585Tg Transgenic Insertion Unknown Unknown DNA
    sa12450 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18662 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa27261 Point Mutation Unknown Missense, Splice Site ENU
    sa41284 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-grk5l N/A 3
    MO2-grk5l N/A 1
    MO3-grk5l N/A 1
    MO4-grk5l N/A 1
    DISEASE ASSOCIATED WITH grk5l HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH grk5l VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process determination of left/right symmetry (more)
    Cellular Component plasma membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA grk5l-201 (1)    Ensembl 2099
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM grk5l No data available
    MARKER RELATIONSHIPS
    grk5l Contained in: [BAC] CH73-322G6 (1), DKEY-220O5 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_005167252 (1)
    Genomic GenBank:CR931937 (1) 174451 nt
    Select Tool
    Polypeptide UniProtKB:F1R6F6 (1) 575 aa
    Sequence Information (all 10)
    ORTHOLOGY for grk5l ( Chr: 8 )
    CITATIONS (23)